A new understanding of Alzheimer’s disease is shaking up what many believed about how this devastating illness takes hold.

Recent research has highlighted the role of the stimulator of interferon genes (STING) signaling pathway in mediating hepatic inflammation and metabolic disorders, making it a potential target for ...

A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a ...

However, our data suggest that 2'3'-cGAMP could also activate Rab18/FosB signaling pathway—but not the well-studied ...

The cGAS-STING signaling pathway, a key element of the innate immune response, has risen as a promising avenue to amplify this therapeutic approach. Unraveling the pathway's role in immune system ...

A study headed by researchers at the Swiss Federal Institute of Technology Lausanne (EPFL) has now shown that a molecular signaling pathway known as cGAS/STING plays a critical role in driving ...

MSK researchers identified a key role for the STING signaling pathway in preventing dormant metastatic cancer cells from progressing to active metastases. Treating laboratory mice with a STING ...

That's how they identified the STING pathway - an acronym for stimulator of interferon genes - as a suppressor of metastatic outbreaks. "This made a lot of sense to us because STING signaling is ...

Moffitt Cancer Center researchers are looking at new targets to help inhibit tumor development and promote antitumor immunity, one being the STING signaling pathway. In a new article published in ...

The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). The activation of cGAS-STING promotes the release and presentation of cancer antigens, T ...