Concurrently, SABER activates STING to increase expression of co-stimulatory molecules, resulting in increased activation of CD8 + T cells when tested in vitro. The authors found that this was ...

Supercharged immunity solves ‘last-mile’ vaccine delivery challenge that could transform battles against cancer, pandemics, ...

Traditional vaccines work by stimulating the immune system, but their effectiveness is often limited by how well they can ...

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). The activation of cGAS-STING promotes the release and presentation of cancer antigens, T ...

China has introduced a groundbreaking vaccine booster, reportedly enhancing immune responses to cancer and infections by up ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...