CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

Concurrently, SABER activates STING to increase expression of co-stimulatory molecules, resulting in increased activation of CD8 + T cells when tested in vitro. The authors found that this was ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses against metastatic pancreatic cancer.

One type of T cell—known as a CD8—is constantly on the prowl in the human body in search of intruders that can cause infections and disease. CD8 T cells transform, or differentiate ...