Writing in the article, Jean E. Sealey D.Sc. states, "Aliskiren’s pervasive stimulation of varying degrees of renin secretion could especially be a problem for those hypertensive patients who ...

Stimulation of renin was seen at levels ... and renovascular hypertension lead to increased BP by excessive secretion of renin. In the latter case, however, measuring plasma renin activity is ...

The (pro)renin receptor ((P ... were constitutively cleaved without any stimulation, and secretion of the amino-terminal fragment (NTF-(P)RR) into the media was determined using western blot ...

Dr. Sequeira-Lopez emphasized that future research would focus on identifying biomarkers and potential therapeutic targets to overcome the harmful effects of chronic stimulation of renin-producing ...

Renin secretion is the initial step in the renin-angiotensin system, which helps regulate blood pressure. Until now, most experts had assumed that only the kidneys could produce renin. The finding ...

"Now we want to identify markers and potential targets to mitigate and hopefully control unwanted effects of chronic ...

UVA’s new discovery offers answers: Excessive stimulation of renin-producing cells in the kidney causes the cells to revert to an invasive, embryonic state. In this state, these cells that line ...

Potassium secretion in this segment is regulated and ... can result from disturbances that originate at any point in the renin–angiotensin–aldosterone system. Such disturbances can result ...

Reninomas are rare renin-secreting kidney tumors, resulting from a neoplastic expansion of juxtaglomerular cells of the kidney, which are cells that regulate blood pressure via the secretion of renin.

e Acquired forms due to either licorice ingestion or ectopic ACTH secretion. f Due to increased ... which suppresses plasma renin activity These disorders should be suspected in young patients ...