Already, the researchers are publishing follow-up scholarship and discovery based on their new breakthrough in understanding the sterol synthesis pathway in the parasites.

University of California - San Diego. "The long pathway to cell organization and growth." ScienceDaily. ScienceDaily, 16 May 2025. <www.sciencedaily.com / releases / 2025 / 05 / 250515132003.htm>.

Caption (A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts ...

Journal reference: Jin, Y., et al. (2024). CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles.

The lipid intermediate pathway shares some molecular constituents with the biochemical pathway used for cholesterol synthesis. “I am extremely honored to have been recognized by the AOCS for my ...