Already, the researchers are publishing follow-up scholarship and discovery based on their new breakthrough in understanding the sterol synthesis pathway in the parasites.

CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles. Nature Communications, 2024; 15 (1) DOI: 10.1038 ...

Caption (A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts ...

Now," concludes Dr. Licinio. More information: Medication-induced sterol disruption: An overlooked threat to brain development and public health, Brain Medicine (2025). DOI: 10.61373/bm025d.0041 ...

Journal reference: Jin, Y., et al. (2024). CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles.

University of California - San Diego. "The long pathway to cell organization and growth." ScienceDaily. ScienceDaily, 16 May 2025. <www.sciencedaily.com / releases / 2025 / 05 / 250515132003.htm>.