A new study looking at the replication stage of the SARS-CoV-2 virus that causes COVID-19 reveals important mechanisms in its replication that could be the foundation for new antiviral therapies.

These viruses have only minutes to establish their replication machinery inside the ... scientists shed new light on these crucial early stages of virus infection and their control.

The method shows a protein named ALIX gets involved during the final stages of virus replication, not earlier, as was believed previously. "We watch one cell at a time" and use a digital camera ...

The virus takes control and destroys certain ... to better understanding the viral lipid composition in the late stages of the replication cycle," Freed cautioned, as many more preclinical studies ...

Known as licensed DNA replication, this controlled process occurs only once each time a cell divides. In contrast, when a virus hijacks a host cell's DNA replication machinery, it replicates ...

The study is published in the journal PLOS Pathogens. With only seven genes, the BK polyomavirus must use the host cell’s DNA replication machinery to produce new viruses. Although the virus was ...

University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their ...

Our understanding of the hepatitis C virus (HCV) life cycle and protein ... the development of direct acting antivirals (DAAs). All stages of the HCV life cycle are potential targets, however ...

8 Thus, EBV probably evolved from a nonhuman-primate virus. The EBV genome consists of a linear DNA molecule that encodes nearly 100 viral proteins. 12 During viral replication, these proteins are ...