HNF1A mutations are found to dysregulate RNA splicing in pancreatic cells, thereby contributing to the onset of diabetes.

This study reports important negative results by showing that genetic removal of the RNA-binding protein PTBP1 in astrocytes is not sufficient to induce their conversion into neurons, challenging ...

Alternative splicing (AS) is a genetic process that increases the diversity of proteins that can be generated from genes, by assembling sections of genetic code into different combinations.

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA).

Alternative splicing (AS) is a fundamental regulatory mechanism in messenger RNA (mRNA) processing, and abnormal splicing is a major cause of genetic disorders.

(B) Proportions of A5SS, A3SS, MXE, RI, SE, and A3SS alternative splicing events in the analyzed T cell subtypes. (C) Shared aging-related alternative splicing events across T cell subtypes.

Teresa Rodriguez-Martin, Mariano A. Garcia-Blanco, S. Gary Mansfield, Andrew C. Grover, Michael Hutton, Qingming Yu, Jianhua Zhou, Brian H. Anderton, Jean-Marc Gallo, Reprogramming of Tau Alternative ...

Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat ...

Alternative Splicing Goes Mainstream In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative ...

Alternative splicing promises to help resolve the question of how 25,000 genes could possibly be enough to encode instructions for a huge range of specialized human cells from osteoplast to neuron.