Thom Graves Media While genome sequencing may be the new kid on the block--perhaps now with a cracking voice and fuzzy facial hair--predicting phenotypes is the stuff of classical genetics, honed on ...

If single-gene disorders are akin to minor misspellings in the human genome, then it stands to reason that the biological equivalent of a word processor's search-and-replace function could correct ...

This would allow us to target every mutation for a disease with a single gene-editing construct ... and therapies for both rare and common diseases," said co-corresponding author Jonathan ...

EULAR - The European Alliance of Associations for Rheumatology - published recommendations on the treatment of familial Mediterranean fever (FMF). Since then, new evidence has become available, so the ...

Regeneron said the study has shown proof-of-concept for its approach that could be extended to other single-gene disorders of hearing. The biotech acquired DB-OTO as part of its $109 million ...

In monogenic disorders caused by mutations in a single gene, height can be severely affected by single-gene variants, often causing severe alterations in stature relative to population averages.

Most human diseases -- including asthma -- are not caused by a single genetic variant, however. Instead, they are the result of complex interactions among multiple genes, environmental factors ...