In this virtual summit brought to you by 10x Genomics, an expert panel will discuss recent advances in combinatorial single cell CRISPR screens and their applications in functional genomics studies ...

At the same time, most screens conducted today rely on rather simplistic read-outs. At Aelian, we use the CROP-seq (CRISPR droplet sequencing) workflow developed by Aelian co-founder Christoph Bock to ...

Looking forward, the researchers are leveraging multimodal single-cell pooled CRISPR screens and mixscape to understand the molecular regulation of dozens of additional pathways and cellular ...

Joseph Replogle, an MD-PhD student in Jonathan Weissman’s lab at the Whitehead Institute/MIT (MA, USA), explains how the technology he worked to develop – direct capture Perturb-seq – has ...

CRISPR screens can be performed either with a pooled ... between the genotype and phenotype. A third option is single-cell CRISPR screening. With this method, a marker similar to a barcode is ...

Recent advances in single-cell technologies have given scientists ... "Integrating chromatin accessibility profiling into the genome-wide CRISPR screens provides a new lens for us to understand ...

Single-cell CRISPR screens bring more information-rich data to drug discovery pipelines, amplifying the number of targets assessed in parallel and providing a direct readout of perturbation effects on ...

While earlier CRISPR screens focused on benchmarking CRISPR ... These may involve combining more than one guide per cell 9 or bringing orthologous CRISPR systems together 10,11 to allow for ...

Single-cell CRISPR screens bring more information-rich data to drug discovery pipelines, amplifying the number of targets assessed in parallel and providing a direct readout of perturbation effects on ...

In this virtual symposium, an expert panel will discuss how advances in single-cell sequencing, fluid-based RNA detection, and functional imaging accelerate biomarker discovery to better understand ...