Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers
In a recent study, precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS ...
Adipocyte-hepatocyte signaling mechanism uncovered in endoplasmic reticulum stress response
The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...
Neuroscience News1d
Protein Imbalance Triggers Autism-Like Behavior
A new study reveals that autism-like symptoms in mice emerge when two nerve proteins—MDGA2 and BDNF—fall out of balance.
eLife13h
Neuronal Signaling: At the crossroads of calcium signaling, protein synthesis and neuropeptide release
By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.
5NRIX : Expert Outlook: Nurix Therapeutics Through The Eyes Of 9 Analysts
Insights from analysts' 12-month price targets are revealed, presenting an average target of $28.56, a high estimate of ...
Disrupted Protein Balance: The Surprising Key to Autism Symptoms
Scientists studying mice have uncovered a delicate protein rivalry in the brain that, when thrown off balance, may cause ...
EurekAlert!3d
How a hidden hand of hepatic signaling could help fight metabolic disease
New research identifies the liver protein PTPRD as a key regulator of metabolic liver disease. Reduced levels of PTPRD disrupt glucose and lipid metabolism, promote liver fat accumulation, and impair ...
A starting signal for cell division: Molecular switch ensures that cells divide at the right time
About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it ...
How nitrate overcomes plant hormone inhibition to boost seed germination
Abscisic acid (ABA), a key environmental response hormone, strongly inhibits seed germination and serves as a central ...