The new drug has already passed Phase 1 safety trials in humans, making it a "strong candidate" for future PTSD treatments.

Researchers discovered that PTSD may be driven by excess GABA from astrocytes, not neurons. This chemical imbalance disrupts ...

The paper also makes a case for GABA-A receptors as a target to treat the cognitive impairment often correlated with depression, but not alleviated by treatments that focus on serotonin or other ...

Excessive levels of GABA released by astrocytes impair the brain's ability to extinguish fear responses in PTSD, but a newly ...

Patients with post-traumatic stress disorder (PTSD) often struggle to forget traumatic memories, even long after the danger ...

GABA receptors in brain could be targets to treat depression and its cognitive symptoms Peer-Reviewed Publication University of Illinois at Urbana-Champaign, News Bureau ...

Serotonin receptors and the 5-HT 4 -type receptors in particular are found in areas throughout the brain, including the frontal cortex, basal ganglia, and hippocampus, that are known to mediate ...

Xu said. Serotonin is primarily synthesized by neurons in the dorsal Raphe nucleus (DRN) in the midbrain. Serotonin neurons in the DRN project to numerous brain regions, including the arcuate of the ...