Melanosis coli is a medical condition caused by the release of a pigment molecule — called lipofuscin — into the mucus membranes of the large intestine (colon). Melanosis coli isn’t life ...

The change, dubbed melanosis coli, is “completely benign”, said ... Dr Rajan explained why this is: “Stimulant laxatives like senna are not meant to be taken long term.

Melanosis coli is a benign pigment disorder in which the lining of the large intestine, or colon, turns black or brown, usually as a result of laxative use. Some research suggests that melanosis ...