Medically reviewed by Michael MacIntyre, MD Schizophrenia medication falls under two main categories: older, first-generation, or "typical" antipsychotics and newer drugs for schizophrenia known as ...

With the exception of aripiprazole and and ziprasidone, second generation antipsychotic drugs induced more weight gain, in various degrees, than did haloperidol, but not than low-potency first ...

Second-generation antipsychotics, which are newer than FGAs, are also called atypical antipsychotics. That’s because they don’t work exactly like typical antipsychotic medications.

The 5 dopamine receptor subtypes (eg, D1, D2, D3, D4, D5) play a role in sodium excretion and blood pressure. Specifically, the D1, D3, and D4 receptors interact with the renin-angiotensin ...

A meta-analysis finds that only 4 of 9 second-generation antipsychotics were more efficacious than first-generation antipsychotics for schizophrenia, with small to medium effect sizes.

Both first- and second-generation antipsychotics affect the risk for TD development because of the way they work on the brain, which involves blocking dopamine receptors (D2 receptors) in the ...

Conventional and new-generation antipsychotics may have similar neurological side-effects NB. Please note that if you are outside North America, the embargo for LANCET press material is 0001 hours ...

Clinically effective dose and binding affinity to D 2 DA receptor were directly correlated for typical antipsychotic medications (r=0.54, p=0.046), but not for second-generation antipsychotic ...