Actin is one of the two major proteins (together with myosin) that form the sarcomere -- the contractile structures of cardiac, skeletal, and smooth muscle cells.

In a heartbeat, cardiac muscle cells contract to push blood out to the body, then relax to allow the heart to fill again. This is possible because muscle proteins are organized into sarcomeres, which ...

The addition of TBX20 promoted cardiac reprogramming, as seen in activation of cardiac genes related to sarcomere structure, ion channels and heart contractions.

Titin is a giant muscle protein with a molecular weight in the megaDalton range and a contour length of more than 1 mm. Its size and location within the sarcomere structure determine its important ...

The addition of TBX20 promoted cardiac reprogramming, as seen in activation of cardiac genes related to sarcomere structure, ion channels and heart contractions.

Setting out to identify all proteins that make up the sarcomere, the basic contractile unit of muscle cells, resulted in an unexpected revelation, providing experimental evidence that helps ...

The muscle does not include a complete sarcomere in the strict sense, as defined by a pair of Z bands, but the equivalent H-H distance reaches about 40 μ m. Electrophysiological evidence suggests that ...