Dr. Magdalena Renne, a leading expert in 3D organoid systems, details how her team has overcome longstanding barriers in ...

Campana cells seem to be a kind of intermediary, transmitting signals from what is seen by rod and cone photoreceptors, which sense light, on to other cells. Campana cells were found to have some ...

In a study using mouse models, researchers found that rod bipolar cells, neurons that normally receive signals from rods that provide night vision, can form new functional connections with cones ...

Photoreceptors in the retinal sheet were then shown to mature properly after transplantation and to make better contact with the host bipolar cells than with normal retinal sheets. Light responses ...

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy. The National Eye Institute, part of the ...

And though researchers had previously observed increased activity in bipolar retinal cells during daylight hours, those measurements were based on observing large populations of cells, Hong added.

The researchers targeted ISLET1, a gene necessary for maturation of bipolar cells that connect to photoreceptors. They began with a line of human stem cells and made clones that lacked the ISLET1 gene ...

“Bipolar cells are downstream from the photoreceptors, so when the MCO1 opsin gene is added to bipolar cells in a retina with nonfunctioning photoreceptors, light sensitivity is restored.” ...

Study: Liquid-biopsy proteomics combined with AI identifies cellular drivers of eye aging and disease in vivo. Image Credit: K illustrator Photo/Shutterstock.com Background Cell-level analyses are ...

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy. The National Eye Institute, part of the ...