Cell surface receptors, such as the G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK), play central roles signalling pathways. Due to their central role in regulating a wide range ...

The study investigates the interaction between the human epidermal growth receptor 2 (HER2) and amygdalin, a compound found ...

5-Prime | Diming Out Dimerization What is dimerization? It is a process where two molecules of similar chemical composition come together to form a single polymer known as a dimer. Where does ...

This illustration shows the estrogen receptor alpha (ERα, in orange) attaching to DNA (in blue) as a pair, or dimer. The image is based on real-time, high-speed atomic force microscopy (HS-AFM) data, ...

Researchers reveal the structural details of apoB100's interaction with LDL receptors, offering insights into LDL dimerization and potential treatments for familial hypercholesterolemia.

New screening process could lead to next-generation therapeutics for a broad spectrum of diseases High-throughput screening provides insight into functional role of key G protein-coupled receptor ...

Scientists at Memorial Sloan Kettering Cancer Center (MSK) have glimpsed never-before-seen details of the human androgen receptor - the protein inside of cells that responds to male-typical ...

Many immune receptors function in pairs called dimers, but to date, PD-1 has been thought to function alone, not in the dimer form. Study results showed that PD-1 forms a dimer through ...

There are a number of G protein-coupled receptors in human cells. As an important component of the cell membrane, these proteins are responsible for detecting different stimuli in the surroundings ...

Scientists at Memorial Sloan Kettering Cancer Center (MSK) have glimpsed never-before-seen details of the human androgen receptor — the protein inside of cells that responds to male-typical hormones ...