The RNP complex is the influenza virus’s essential package, the virus’s blueprints and a copy machine all rolled in one. The ...

Synthetic RNA platforms allow for rapid, scalable, and cell-free manufacturing of a variety of biologic therapeutics. A development pipeline is based on in vitro transcription of target protein ...

This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

Experiments have shown that TFs can bind tightly, both within cells and in vitro ... TFs and whether they attract RNA polymerase or block it from initiating transcription. Multiple TFs can ...

More information: Tanja Bhuiyan et al, TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing factors, Cell Reports (2025). DOI: 10.1016/j.celrep.2025.115616 ...

When exposed to blue light, this transcription factor induces guide RNA (gRNA) in cells ... and precise base editing in cells in vitro. They also incorporated the light-induced CRISPR system ...