Researchers have developed BigRNA, a groundbreaking deep learning model capable of predicting RNA behavior, including tissue-specific expression and splicing, directly from genomic DNA sequences ...

A group of Australian scientists has uncovered a new way to fight some of the toughest cancers by targeting an overlooked ...

Deep Genomics has shown that our unique AI foundation model, BigRNA, can utilize DNA sequences to accurately discover the effects of non-coding, missense and synonymous variants on tissue-specific ...

Building proteins RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts that carry the instructions for building proteins.

The modulation of RNA splicing by small molecules has emerged as a promising strategy for treating pathogenic infections, human genetic diseases, and cancer; however, the principles by which ...

Building proteins RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts that carry the instructions for building proteins.

Conclusions To summarize, the study identified RNA splicing errors as a major source of tumor-specific neoantigens in gliomas, offering new opportunities for targeted immunotherapy.

Antisense therapy restores fragile X protein production in human cells Aberrant alternative splicing of messenger RNA plays fundamental role in fragile X syndrome Date: July 5, 2023 Source: UMass ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are ...