Pamela J. Camp, Douglas D. Randall, Purification and Characterization of the Pea Chloroplast Pyruvate Dehydrogenase Complex: A Source of Acetyl-CoA and NADH for Fatty Acid Biosynthesis, Plant ...

The study found that among the genes encoding components of the pyruvate dehydrogenase complex, which controls acetyl CoA synthesis, only dlat-1 and dld-1 expressions were decreased by 6-PPDQ.

Pyruvate dehydrogenase complex is associated with intact chloroplasts and mitochondria of 9-day-old Pisum sativum L. seedlings. The ratio of the mitochondrial complex to the chloroplast complex ...

The study also demonstrated that the disruption in citric acid cycle and reduction in acetyl CoA and pyruvate contents contributed to mitochondrial dysfunction, as indicated by increased oxygen ...