In April 2025, the FDA granted orphan drug designation to spesolimab-sbzo for the treatment of pyoderma gangrenosum. This ...

Pyoderma gangrenosum is an ulcerating disorder of the skin with sterile neutrophilic inflammation that may be seen in up to 5% of patients with chronic ulceration of the legs. 1 Typically painful, it ...

Ulcerative pyoderma gangrenosum is a rare inflammatory disease with an incidence of 3–10 cases per million per year. 1 Consideration of the diagnosis is based on its classic morphological features: ...

Following the recommendation, InflaRx intends to halt further development of vilobelimab for the PG indication. The company ...

A 35-year-old woman was referred urgently to the dermatology department because of significant wound breakdown 3 weeks following an emergency caesarean section. Examination revealed a full thickness, ...

Pyoderma gangrenosum is a rare condition of unknown etiology that was described as an extraintestinal manifestation of inflammatory bowel disease in 1930. At present, there are few well-designed ...

Pyoderma gangrenosum is an uncommon type of cutaneous ulceration that continues to be a difficult disorder to diagnose and treat 11. It is a neutrophilic dermatosis associated in 70% of the cases with ...

We present a case of pyoderma gangrenosum (PG) affecting the breast of a 74-year-old woman, with a history of breast cancer treated with breast conserving surgery and adjuvant radiotherapy 17 years ...

Pyoderma gangrenosum is an inflammatory condition that starts as a rapidly enlarging, very painful ulcer, usually due to a condition like Crohn's. It is thought to affect one in 100,000 in the UK ...

Pyoderma gangrenosum is an uncommon type of cutaneous ulceration that continues to be a difficult disorder to diagnose and treat 11. It is a neutrophilic dermatosis associated in 70% of the cases with ...