The sequence of amino acids in a protein, known as its primary structure, determines its unique three-dimensional shape and function. Proteins can further fold and assemble into complex structures, ...

‘AI-based protein design effectively enabled us to dream small proteins into existence that would bind ChuA,’ says Grinter.

The research team claims that the protein amino acid sequences generated by EvoDiff cover the entire structural, functional, and sequence spatial characteristics of proteins that exist in nature.

Proteins are the workhorses of our cells, yet we simply don't know what proteins we all carry with us. A protein is a long peptide string made of 20 different types of amino acids, comparable to a ...

Amino acid analysis aids in confirming the sequence and structure of proteins. By comparing the experimentally determined amino acid composition with the predicted composition based on genetic ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are ...

A team of researchers led by Penn State chemists modeled how genetic changes that alter the speed of protein synthesis, but not the sequence of amino acids that comprise the protein, can lead to ...