Laser-induced alignment boosts single-particle imaging by improving molecular orientation, enabling clearer 3D structure recovery of proteins and macromolecules. (Nanowerk News) Single-particle ...

Alexander Rives, Joshua Meier, Tom Sercu, Siddharth Goyal, Zeming Lin, Jason Liu, Demi Guo, Myle Ott, C. Lawrence Zitnick, Jerry Ma, Rob Fergus, Biological structure and function emerge from scaling ...

Typically, figuring out the structure involves laborious biochemistry to purify the protein, followed by a number of imaging techniques to determine where each of its atoms resides. But in theory ...

Predicting proteins’ structure from their amino acid sequences had stumped researchers since the 1970s. But in 2020, Hassabis and Jumper developed an artificial intelligence model called AlphaFold2.

In the current study, the researchers computationally demonstrated that nanoparticles and proteins can be strongly aligned utilizing conventional laser technology. After analyzing 150,000 proteins ...

Scientists David Baker, Demis Hassabis and John Jumper won the 2024 Nobel Prize in Chemistry, the award-giving body said on Wednesday, for work on the structure of proteins.