Discover how automation is transforming protein purification, reducing costs and accelerating biopharma drug development.

Discover essential antibody purification methods, from affinity chromatography to ion exchange chromatography, for research ...

Understanding and characterizing complex compounds is essential for drug discovery and development. Chromatography is a vital ...

Manual protein purification techniques, such as those based on the use of spin and gravity-flow columns, are burdened, in part, by the lack of standardized affinity tag purification protocols.

As QbD concepts infiltrate protein development and manufacturing, small-scale and early-stage protein isolation will be viewed as a warm-up for pilot and large-scale purification.

Self-removing tags can be used for simple and effective purification of recombinant proteins and peptides. The key component of these tags is an intein, which is a protein element with the ability to ...

Credit: Mararie, CC-BY-SA-2.0 Traditional protein purification relies heavily on chromatography, a method that separates proteins based on their size.

Proteins, and their little sisters the peptides, are among the most difficult compounds to purify. Enzyme degradation and chemical decomposition conspire to ruin protein samples throughout the steps ...

Protein purification Antibodies and other protein drugs are part of a growing class of drugs known as biologics, which also include molecules such as DNA and RNA, as well as cell-based therapies.

Such proteins are isolated from natural sources or produced with the help of genetically modified cells. To this end, affinity chromatography has been the method of choice since 50 years.

These structural features impart high hydraulic permeability, rapid mass transfer and mechanical flexibility, which render cryogels exceptionally well suited for applications in protein purification.