One of the challenges in biopharmaceutical development is measuring the 3-d structure of the active protein. The diffraction of X-ray beams through a crystalline structure can be measured to produce a ...

“We were a good match because Martin and his group are interested in dynamics,” said Scaletti. “Not just the spatial structure of the protein but how it changes over time, and that seemed like a ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

Another is to map a protein’s 3D structure and—with a dose of physics—predict how it can grab onto other molecules. While AlphaFold 2 mostly used an evolutionary approach—training the AI on what we ...

In the present study, researchers used the recent release of the AlphaFold2 database of protein structure predictions to enable reverse docking approaches that span Escherichia coli's (E.coli ...

There’s an age-old adage in biology: structure determines function. To understand the function of the myriad proteins that perform vital jobs in a healthy body—or malfunction in a diseased one ...

Move over, chatbots. This upgraded AI can model antibodies, DNA, and molecules from disease organisms. This next generation of AlphaFold, from Google Deepmind, is poised to significantly advance ...