Mitogen-Activated Protein Kinase (MAPK) signalling pathways represent a fundamental means by which cells translate extracellular stimuli into a wide array of intracellular responses, including ...

B Signaling NEGATIVE FEEDBACK:© AAASNF-κB is held inactive in the cytoplasm by three IκB isoforms. Cell stimulation activates the kinase IKK which leads to phosphorylation and degradation of IκB. This ...