Transcription begins with the binding of RNA polymerase to a specific sequence of DNA called the promoter. Promoters are located upstream of the gene and contain recognition sites for the polymerase ...

Each gene in our DNA has a beginning and an end. Defining the gene’s extremities properly is crucial to produce functional protein. A lot of research has been done on finding out what determines when, ...

How to Identify Gene Promoters and Enhancers by ChIP-Seq Summary Chromatin immunoprecipitation (ChIP) is an effective method for isolating DNA fragments bound to specific proteins in vivo. DNA-binding ...

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer.

New technique reveals how gene transcription is coordinated in cells By capturing short-lived RNA molecules, scientists can map relationships between genes and the regulatory elements that control ...

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a ...

As an example, the researchers focused on a gene called Nanog, a 770,000-base length of DNA on chromosome 6, which has a promoter and three enhancer regions and is known to undergo transcriptional ...

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a ...

Study shows how ALS-linked mutations disrupt the protein TDP-43 at the atomic level, preventing it from executing its ...