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Key mechanism for maintaining proper telomere length identifiedResearchers at Rockefeller showed that this process is mediated by two enzymes: telomerase and the CST–Polα/primase complex. Having determined how telomerase is recruited, scientists were left ...
Primase, eine an der DNA-Synthese (Replikation) beteiligte spezifische RNA-Polymerase, die die Synthese eines kurzen RNA-Abschnitts katalysiert, der komplementär zu einem der DNA-Matrizenstränge ist.
How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is to find proteins that directly bind to both enzymes.
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