Hosted on MSN2mon
Key mechanism for maintaining proper telomere length identifiedResearchers at Rockefeller showed that this process is mediated by two enzymes: telomerase and the CST–Polα/primase complex. Having determined how telomerase is recruited, scientists were left ...
Hosted on MSN12mon
Assembly Bio to launch four infectious disease trials in 2024In H1, the company hopes to initiate a first-in-human (FIH) trial of its candidate ABI-5366, a helicase-primase inhibitor targeting patients with HSV2, specifically recurrent genital herpes.
How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is to find proteins that directly bind to both enzymes.
Primase, eine an der DNA-Synthese (Replikation) beteiligte spezifische RNA-Polymerase, die die Synthese eines kurzen RNA-Abschnitts katalysiert, der komplementär zu einem der DNA-Matrizenstränge ist.
Results that may be inaccessible to you are currently showing.
Hide inaccessible results