Prader-Willi syndrome is caused by changes in gene expression in a specific portion of chromosome 15. Starting in childhood, it often leads to extreme, insatiable hunger.© Catherine Falls ...

"EMA validates Soleno’s application for Prader-Willi syndrome treatment" was originally created and published by Pharmaceutical Technology, a GlobalData owned brand.

Prader-Willi syndrome, which strikes only 1 in 15,000 people, can cause learning issues, muscles weakness, a slow metabolism and an insatiable appetite.

People enrolled in the study were 4 years old or older with Prader-Willi syndrome and excessive hunger and had already been taking Vykart XR for an average of 3.3 years (range: 2.5 to 4.5 years).

Prader-Willi syndrome is the most common genetic cause of obesity that has been identified, affecting upwards of 400,000 people worldwide, according to epidemiological research.

In a comprehensive Genomic Press Invited Expert Review, researchers from the University of Haifa have synthesized cutting-edge findings on Prader-Willi syndrome (PWS), revealing how this complex ...

Prader-Willi syndrome (PWS) is a rare genetic disorder that develops due to the deletion of chromosome 15. People with PWS may experience poor growth and low muscle tone in childhood, low muscle ...

In patients with Prader-Willi syndrome, DCCR is expected to reduce hyperphagia through activation of the adenosine triphosphate–sensitive potassium channels in the hypothalamus.

Stefan Stamm and Shivendra Kishore, of the Friedrich-Alexander University Institute for Biochemistry, suggest that HBII-52, a non-coding RNA located on chromosome 15 regulates alternative splicing of ...

Federal regulators are clearing a first-of-its-kind treatment for symptoms of a rare neurodevelopmental disorder that is characterized by insatiable hunger. The Food and Drug Administration approved a ...

Diazoxide choline is the first drug indicated for hyperphagia in the rare genetic disorder. Prior to approval, people with Prader-Willi had to rely on strict dieting and off-label obesity medications.