A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...
Two heads are better than one, as the saying goes, and sometimes two instruments, ingeniously recombined, can accomplish feats that neither could have done on its own.
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The research is published in Proceedings of the National Academy of Sciences ("Volumetric imaging of the 3D orientation of cellular structures with a polarized fluorescence light-sheet microscope").