Provide an overview of the renin-angiotensin-aldosterone system (RAAS) and implication on Hypertension. Describe and understand key differences between plasma renin activity (PRA) assays and direct ...

Baxdrostat is a highly selective, second-generation, nonimidazole aldosterone synthase inhibitor; 100 times less baxdrostat ...

Traditionally, renin is measured by a plasma renin activity (PRA) radioimmunoassay or liquid chromatography tandem mass spectrometry (LC-MS/MS). However, newer quantitative renin mass immunoassays ...

We have found that the most sensitive and specific screening test for primary aldosteronism is the plasma aldo-sterone-to-plasma renin activity ratio obtained from peripheral blood during the ...

At both 1 and 6 weeks, levels of plasma aldosterone (baseline median, 134 pmol/L), direct renin concentration (median, 20 mU/L), renin activity (median, 2.2 ng/mL per hour) and ARR using either ...

(HealthDay)—A suppressed renin phenotype is associated with higher incidence of incident hypertension than other plasma renin activity (PRA) phenotypes, according to a study published online Oct ...

Patients with primary aldosteronism also saw an increased risk for both atrial fibrillation (OR = 3.52; 95% CI, 2.06-5.99) and heart failure (OR = 2.05; 95% CI, 1.11-3.78) compared with those who ...

In the seated position, morning plasma aldosterone level was increased (557 pmol/l, standard value <415 pmol/l), concurrently measured plasma renin activity was decreased (<0.3 μg/l/h; standard ...

Peripheral plasma renin activity was measured in 11 patients with terminal renal failure supported by chronic hemodialysis while they were awaiting transplantation. In 3 of these 11 patients the ...