Traditionally, renin has been measured by a plasma renin activity (PRA) radioimmunoassay or liquid chromatography tandem mass spectrometry (LC-MS/MS). Direct renin concentration (DRC) immunoassays, ...

Baxdrostat is a highly selective, second-generation, nonimidazole aldosterone synthase inhibitor; 100 times less baxdrostat ...

VANCOUVER, B.C.—High plasma renin activity (PRA) is associated with adverse renal outcomes in patients with coronary artery disease (CAD), according to study findings presented at the World ...

We found that the patient’s plasma metanephrines were normal; however, her plasma renin was 12.0 (normal 0.3–2.2) nmol/L/h, her aldosterone was 1765 (normal < 630) pmol/L and her aldosteroneto-renin ...

Renin release is minimal in the hypothyroid state, in part owing to decreased renal β-adrenergic activity. [37, 38] Kobori et al. reported that thyroid hormone stimulates renin gene expression in ...

Low plasma renin activity due to volume expansion is a feature common to these disorders; the disorders can be characterized further into syndromes of increased or decreased aldosterone synthesis.