In addition, the researchers discovered that plasma cells secreting anti-CD19 bispecific antibodies elicited antitumor activity, as demonstrated with acute lymphoblastic leukemia patient-derived ...

Multiple myeloma is a type of blood cancer that begins in plasma cells found in the bone marrow. About 20% of patients have a genetic change called t (4;14), which makes the NSD2 gene highly active.

The CAR T cell therapy, called NXC-201, targets a protein called BCMA, which is expressed on the surface of amyloid plasma cells and drives cancer growth. In the first 10 patients to receive the ...

Germinal center B-cell–like diffuse large B-cell lymphomas (GCB-DLBCLs) show dependence on DOT1L and EZH2, with combined targeting offering potential as an alternative differentiation-based therapy.

A “complete eradication” of B cells with chimeric antigen receptor T-cell therapy is responsible for the long-term, drug-free remission from autoimmune diseases observed after treatment ...

Distinct mural cells and fibroblasts promote pathogenic plasma cell accumulation in idiopathic pulmonary fibrosis. European Respiratory Journal, 2025; 2401114 DOI: 10.1183/13993003.01114-2024 ...

SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination. Nature Medicine, 1-10.

Partnership aims to accelerate precision immunotherapy by leveraging AI-powered virtual cell models to identify which patients are most likely to benefit from BOT/BAL treatment Collaboration ...

Inductively coupled plasma mass spectrometry (ICP-MS) is prominently used for analyzing elemental composition in individual cells. However, the conventional sample introduction system of ICP-MS ...