Engineered plasma cells show long-lasting antileukemic activity in mice Date: July 2, 2024 Source: Cell Press Summary: Researchers show for the first time that engineered human plasma B cells can ...

In addition, the researchers discovered that plasma cells secreting anti-CD19 bispecific antibodies elicited antitumor activity, as demonstrated with acute lymphoblastic leukemia patient-derived ...

Multiple myeloma is a type of blood cancer that begins in plasma cells found in the bone marrow. About 20% of patients have a genetic change called t (4;14), which makes the NSD2 gene highly active.

Germinal center B-cell–like diffuse large B-cell lymphomas (GCB-DLBCLs) show dependence on DOT1L and EZH2, with combined targeting offering potential as an alternative differentiation-based therapy.

The CAR T cell therapy, called NXC-201, targets a protein called BCMA, which is expressed on the surface of amyloid plasma cells and drives cancer growth. In the first 10 patients to receive the ...

Distinct mural cells and fibroblasts promote pathogenic plasma cell accumulation in idiopathic pulmonary fibrosis. European Respiratory Journal, 2025; 2401114 DOI: 10.1183/13993003.01114-2024 ...

LEXINGTON, Mass. & SAN FRANCISCO, June 17, 2025--Agenus and Noetik Enter Collaboration to Develop AI-Enabled Predictive Biomarkers for BOT/BAL Using Foundation Models of Virtual Cell Biology ...