Diffusion-weighted imaging (DWI) identifies bioenergetically compromised tissue, and perfusion-weighted imaging (PWI) allows visualization of hypoperfused tissue. 4,5 Mismatch between a larger PWI ...

Background: Reperfusion in stroke patients with a perfusion-diffusion (PWI-DWI) mismatch leads to better clinical outcomes (1). Because some patients cannot receive gadolinium contrast agents, we ...

Introduction The combination of MRI diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) maps is used to assess PWI/DWI mismatch, which provides an estimate of the volume of penumbral ...

The Desmoteplase in Acute Ischemic Stroke Trial (DIAS-1) looked at patients who were 3 to 6 hours out from stroke onset and had a perfusion/diffusion mismatch on imaging of 20% or greater (Stroke ...

PIM – mismatch between perfusion deficit and ischemic core: Mismatch ratio >1.8, mismatch volume >15 ml, core volume <70 ml, as determined by 3 different measures to define the perfusion deficit (DT ...

After having been selected by the so-called perfusion/diffusion "mismatch" present on MRI, 38 patients were randomized.

“With acute ischemic stroke, we are familiar with the fact that a large proportion of patients have a mismatch between a larger perfusion and a smaller diffusion lesion, typically associated ...

Copen et al. Existence of the Diffusion-Perfusion Mismatch within 24 Hours after Onset of Acute Stroke: Dependence on Proximal Arterial Occlusion. Radiology, 2009; DOI: 10.1148/radiol.2503080811 ...

When you breathe, a certain fraction of your air enters the lungs and blood flows through the capillaries. When this ratio is above or below 0.8, you may have ventilation/perfusion (V/Q) mismatch.

Perfusion–diffusion mismatch patterns on MRI can be used to select patients with acute stroke who might benefit from off-label thrombolytic therapy within an extended time window of at least 6 h ...

Stroke patients presenting 6 to 24 hours after they were last known well could enjoy reductions in 90-day disability after thrombectomy whether they had qualified by clinical mismatch (OR 3.57, 95 ...

Stroke 39, 1898–1900 (2008). Article CAS Google Scholar Butcher, K. S. et al. Refining the perfusion-diffusion mismatch hypothesis. Stroke 36, 1153–1159 (2005). Article CAS Google Scholar ...