Researchers have discovered a novel gut-brain sensory circuit in mice where specialized colonic cells sense bacterial flagellin and rapidly suppress feeding via the vagus nerve. This "neurobiotic ...

Immunostimulants also activate other pattern recognition receptors (PRRs) like retinoic acid-induced gene I (RIG-I), nucleotide-binding oligomerization domain 1 (NOD1), nucleotide-binding ...

Scientists are using AI and genetic engineering to enhance plant immunity, offering a new defense against crop diseases.

Host defenses rely on innate immunity, a rapid response based on pattern recognition, and adaptive immunity, a more slowly developing specific antigen-recognition system. This review summarizes fea ...

New gut study shows specialized colonic cells use pattern recognition receptors to sense bacterial protein and trigger rapid brain signaling.

Host pattern recognition receptors (PRRs) are crucial for sensing pathogenic microorganisms, initiating innate responses, and modulating pathogen specific adaptive immunity during infection.

Scientists at the National Institute of Biological Sciences, Beijing report that two pore-forming proteins from the common ...

Natural pattern-recognition-receptor agonists in prophylactic vaccines for in situ vaccination of lymphoma. Authors: Mark Aleynick, Paul Peng, Linda Hammerich, Antoine Tanne, Judith Agudo, Brian D.