Epidemiological studies have provided extensive evidence for an association between advanced paternal age (APA) at conception and a series of negative outcomes in offspring. These adverse effects ...

In a recent study published in the Fertility and Sterility journal, researchers assessed the effects of paternal age on novel mutations and diseases in the next generation. Study: The impact of ...

Separately, they investigated whether the effects of paternal age on development were more likely attributable to genetic or environmental factors. The researchers found that children born to very ...

Second, we have a large gap in our knowledge regarding the importance of paternal age effects because most research only focuses on maternal age. (This is for practical reasons: mothers are easier ...

Known as the paternal age effect, numerous studies have suggested that the older a man is when he reproduces, the increased likelihood that his children will develop birth defects or health ...

Paternal age and the health effects it has on potential offspring have been the focus of many studies, but few have examined the effect parental age has on the risk of adult-onset hormone-related ...

More recent evidence shows that a man's age does affect both fertility and the child's health. "Advanced paternal age" has been linked to miscarriages, birth deformities, cancer, and specific ...

The findings appear in JAMA Psychiatry. "Paternal age may have a stronger effect than we previously realized," says Brian D'Onofrio, the study's lead author and an associate professor of ...

Though research suggests that the paternal-age effect is most significant for fathers over 40, younger fathers may also face an increased risk, possibly because spermatogenesis in very young ...

Nonetheless, not much has been known about the effects of advanced paternal age on pregnancy and their offspring until relatively recently. Instead, overwhelming focus has been put on the maternal ...

"It has become increasingly clear that advanced paternal age, just like advanced maternal age, is associated with… poor health effects in offspring," the Utah researchers write. Researchers at ...