New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...

When p53 malfunctions, the result is often cancer. Learning about how p53 works has not only deepened how scientists understand cancer, but also provided promising avenues for new treatments.

New research illustrates how a DNA repair protein suppresses senescent cells, reducing age-associated chronic inflammation.

Although there are tumor suppressor genes in normal cells to prevent cancer, gene mutations can cause a normal cell to become ...

Munoz, and Fred Bunz from the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine studied the tumor-suppressing protein p53, which plays a key role in ...

Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolism ...

Munoz, and Fred Bunz from the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine studied the tumor-suppressing protein p53, which plays a key role in ...

New findings show that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like ...

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against ...

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...