Obese women with regular menstrual cycles have subdued ovarian follicle development and less production of reproductive hormones, stated a new study. The decreased hormonal production may underlie ...

Aritro Sen, Hen Prizant, Allison Light, Anindita Biswas, Emily Hayes, Ho-Joon Lee, David Barad, Norbert Gleicher, Stephen R. Hammes, Androgens regulate ovarian follicular development by increasing ...

This collective aggregate that eventually produces a mature egg cell is called the ovarian follicle. "While we have been able to artificially make mouse oocytes from stem cells, for them to mature we ...

BOSTON -- For the first time, researchers have shown how Mullerian inhibiting substance (MIS), also known as anti-Mullerian hormone, a key reproductive hormone, suppresses follicle development and ...

Ovarian follicles are essential for female fertility, forming during fetal development and establishing a finite reserve of approximately one million primordial follicles. Each follicle contains ...

Women with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive hormones, which may underlie reduced fertility ...

In the interests of transparency, eLife publishes the most substantive revision requests and the accompanying author responses. Chen and colleagues analyze the function of methyltransferase PRMT5 in ...

Significance was defined as * P < 0.05, ** P < 0.01, *** P < 0.001 and **** p < 0.0001. Results Prolonged estrus cycle in rats induced by adult-onset hypothyroidism To investigate the effect of ...

Reference: Yoshino T, Suzuki T, Nagamatsu G, et al. Generation of ovarian follicles from mouse pluripotent stem cells. Science. 2021;373 (6552):eabe0237. doi: 10.1126/science.abe0237 This article has ...