Outbred stocks of rats and mice are commonly used in academic and industrial research. We estimate that from January 2002 to July 2005 ∼33% of all mouse papers and 85% of all rat papers in the ...

Scientists have developed an animal model of scrub typhus using outbred CD-1 mice. Using the model, they have characterized host susceptibility to the causative pathogen, disease pathogenesis ...

A genetically diverse mouse model is able to predict the range of response to chemical exposures that might be observed in human populations, researchers from the National Institutes of Health (NIH) ...

In 2009 Churchill's lab started the Diversity Outbred mouse population with breeding stock selected from the Collaborative Cross project. The research team estimates that the standard laboratory ...

Scientists relied on Diversity Outbred mice, a population from eight parents created by The Jackson Laboratory to better reflect genetic diversity in humans. The Dlgap2 study involved 437 mice ...

In 2009 Churchill's lab started the Diversity Outbred mouse population with breeding stock selected from the Collaborative Cross project. The research team estimates that the standard laboratory ...

The current study's researchers investigated the effects of both CR and IF on the health and lifespan of female diversity outbred (DO) mice. Notably, DO mice are genetically diverse, which allows ...

in female diversity outbred (DO) mice. The study was designed to ensure that each mouse was genetically distinct, which allowed the team to better represent the genetic diversity of the human ...