Arginase deficiency is a rare autosomal recessive metabolic disorder that disrupts the final step of the urea cycle, impairing the conversion of arginine into urea and ornithine. In affected ...

Lee: Arginase deficiency is a rare genetic disease caused by the absence of arginase 1, a urea cycle enzyme that converts the amino acid arginine to ornithine. When the body cannot process ...

International: 1-201-689-8560 Conference ID: Arcturus Webcast: Link About Ornithine Transcarbamylase Deficiency Ornithine transcarbamylase (OTC) deficiency is the most common urea cycle disorder.

Rat Studies Sprague—Dawley rats, weighing between 300 and 650 gm, were injected intraperitoneally with 5 ml of 0.5 M solutions of urea, arginine and creatinine, and 5 ml of 5.0 M urea.

New FDA-approved formulation for patients living with urea cycle disorders $42.5 million of non-dilutive debt funding available to Acer that, if drawn, would extend cash runway into H2 2023 NEWTON ...

The Food and Drug Administration (FDA) has granted Orphan Drug designation to ARCT-810 (Arcturus Therapeutics), a novel treatment for ornithine transcarbamylase deficiency (OTCD), a urea cycle ...