More than 3 million Americans have glaucoma, which results from damage to the optic nerve, causing blindness in 120,000 U.S. patients.

The mice served as a model for children with the genetic condition neurofibromatosis type 1 (NF1). About one in six children with NF1 develops low-grade optic nerve tumors by age 7.

Citation: Smith et al., SOCS3 Deletion Promotes Optic Nerve Regeneration In Vivo, Neuron (2009), doi:10.1016/ j.neuron.2009.11.021 ...

“Suppression of 40 genes using viral-driven short hairpin RNAs promotes retinal ganglion cell axon regeneration after optic nerve crush, and most are validated by separate CRISPR-Cas9 editing ...

Researchers have developed a laser-based artificial neuron that fully emulates the functions, dynamics and information processing of a biological graded neuron. With a signal processing speed of ...

CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism. Neuron, 2022; DOI: 10.1016/j.neuron.2022.10.025 ...

Pituitary tumors can compress the optic nerve, leading to visual symptoms. Pituitary tumors are mostly benign (noncancerous), but due to their location, they can have significant effects on ...

Nonarteritic anterior ischemic optic neuropathy, or NAION, is a rare condition that afflicts 2 to 10 out of 100,000 people. Like a brain stroke, the condition occurs from reduced blood flow to the ...

Damage to the optic nerve can lead to irreversible blindness. A newly investigated regeneration factor could change that, UConn researchers report in the May 2024 issue of Experimental Neurology.

Prior to this study, there was no treatment that allowed for damage to the optic nerve to be reversed. Around 500,000 people are living with glaucoma in the UK and it’s the second leading cause ...

The mice served as a model for children with the genetic condition neurofibromatosis type 1 (NF1). About one in six children with NF1 develops low-grade optic nerve tumors by age 7.