Certain medications can cause onycholysis as a side effect. Chemotherapy drugs, antibiotics, and other medications can affect nail growth and structure, leading to separation in some individuals.

Onycholysis is usually painless and may appear several months after having COVID. Outside of COVID, you can develop onycholysis from getting manicures, fungal infections, and psoriasis.

Between August 2002 and September 2003, 45 patients were evaluated. Onycholysis and skin toxicity were significantly lower in the FG-protected hand compared with the control hand (P = .0001).

A total of 128 patients (average age, 46.1 years; range, 8-84 years) with nail psoriasis, onychomycosis, idiopathic/traumatic onycholysis, brittle nail syndrome, nail lichen planus, retronychia ...

Session ID: 2025-06-19:8b71061a75fd8cddbdee2e86 Player Element ID: V7bb74188_a3ce_4f9c_888b_e7165021e2e5_6329971094112 ...

Onycholysis can also be caused by using products that contain high levels of certain ingredients. "Particularly HEMA [hydroxyethyl methacrylate, an ingredient used to make resin," explains McNails.