Oligodendrocyte density and identification varied between gerbil and Etruscan shrew indicating species-specific differences. We found that S100-labeling allows differentiation and quantification of ...

Study uncovers how environmental chemicals, specifically organophosphate flame retardants and quaternary compounds, negatively affect oligodendrocyte development, implicating them in potential ...

Lipopolysaccharide-activated microglia induce death of oligodendrocyte progenitor cells and impede their development. Neuroscience 166, 464–475. doi: 10.1016/j.neuroscience.2009.12.040 ...

In a healthy CNS, oligodendrocyte precursor cells (OPCs) migrate to sites of demyelination and produce oligodendrocytes. However, this process is disrupted in demyelination disorders such as multiple ...

New cause of brain defects in tuberous sclerosis complex Date: February 9, 2017 Source: The Rockefeller University Press Summary: A new molecular pathway that inhibits the myelination of neurons ...

Oligodendrocyte development continues from before birth into adulthood, and so these cells may be especially at risk of damage from toxic chemicals. Paul Tesar and colleagues examined the effects of 1 ...

Moreover, GW3965 encourages oligodendrocyte development and myelination, both of which enhance cognitive and emotional processes to ultimately ameliorate depression-like behaviors.

Early in the pathogenetic process, oligodendrocyte development is impaired and oligodendrocyte survival diminished (2). Axons are also damaged in PVL (2), but when this process is initiated is not ...