SLN evaluation allows for increasingly sensitive detection of nodal metastasis, which has created the dilemma of how best to treat patients with occult metastasis in a way that will maximize ...

Studies will need to validate, in a new patient cohort, the prognostic utility of GUCY2C qRT-PCR for categorical identification (yes/no) of occult metastases as a marker of disease recurrence.

Short-term ADT especially benefitted patients with a baseline PSA level of more than 2 ng/mL, a PSA doubling time of less than 3 months, and a higher metastatic stage, presumably because they were ...