HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer.

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a ...

Luo et al. found that IGFBP2, a biomarker associated with copper metabolism, is not only a glioma tumor promoter that promotes disease progression, but also affects immunotherapy response. Studies ...

Targeting nucleotide metabolism also provides new directions, for the development of novel antitumor-specific drugs (10, 11). Furthermore, the onset and advancement of several cancers are ...

Despite the significant advances in our understanding of nucleotides and their roles in living organisms, several challenges remain. One of the main challenges is the complexity of nucleotide ...

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A new screening system developed by scientists at the UCLA Jonsson Comprehensive Cancer Center leverages redundancy in an important component of a cell -- nucleotide metabolism -- to help identify ...

One potential candidate for a protein responsible for the transthylakoid transport is the detected 36.5-kDa nucleotide-binding protein, as supported by two observations: (i) this thylakoid protein ...