Peptide nucleic acids (PNAs) represent a revolutionary class of synthetic nucleic acid analogues, in which the traditional sugar–phosphate backbone is replaced by a neutral N-(2-aminoethyl ...

An Introduction to Structural Biology. Credit: Technology Networks via YouTube What is structural biology? Structural biology is a field dedicated to the study of the structure of molecules that form ...

Nucleic acids research continues to have a major impact on a wide range of fields at the key interfaces between chemistry, the life science and physics, with applications ranging from DNA chips and ...

Mass spectrometry-based proteomics methods are finding increasing use in structural biology research. Beyond simple interaction networks, information about stable protein-protein, protein-ligand or ...

Subject Areas Nucleic Acids as therapeutics (including antisense, RNAi, aptamers, immune recognition, cell delivery) RNA and DNA structures, their complexes and drug targets (duplexes, quadruplexes, ...

An innovative programmable tool for targeting nucleic acids has been created, utilizing a prokaryotic immune defense system—and it is not CRISPR-Cas. Russian Academy of Sciences researchers have ...

University of Queensland researchers have developed an affordable, open-source DNA measurement tool that can be built using a ...

A research team describes how they engineered an efficient new enzyme that can produce a synthetic genetic material called threose nucleic acid. The ability to synthesize artificial chains of TNA ...

Purdue University researcher David Thompson has developed LENN, a system to deliver nucleic acid-based therapies to targeted cancer cells. His and his team’s research into using LENN to deliver ...