The structure and chemistry of nucleic acids is fundamental to their function, from the DNA double helix discovered by Watson and Crick to the intricate secondary and tertiary structures adopted by ...

If you are studying nucleic acid structures in your lab, you may apply several methods to identify and characterize G4 structures and confirm their formation in your samples.

The team’s findings published in ACS Applied Materials & Interfaces ("Immunostimulation of Fibrous Nucleic Acid Nanoparticles Can be Modulated through Aptamer-Based Functional Moieties: Unveiling the ...

Nucleic acid extraction is a fundamental step in unlocking the genetic information contained within biological samples. Isolated nucleic acids are the basis for a multitude of analyses and ...

If possible, targeting noncanonical nucleic acid structures with PNAs would increase the chance of developing novel therapeutics that can target all genomic DNA and RNA structures in genes and ...

More information: Lara M. Mollé et al, Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery, WIREs Nanomedicine and Nanobiotechnology (2022).

G4s and R-loops,” he says. “ Non-canonical nucleic acid structures were noticed to be increased in cancer cells already, but this paper has established a better-defined connection.” Anjana Rao, a ...