"The importance of deoxyribonucleic acid (DNA) within living cells is undisputed" (Watson & Crick, 1953). This opening sentence of James Watson and Francis Crick's second major paper, published ...

For example, if you feed linear nucleic acids to human cells, they will reject them. The reason behind this is that the cell membrane is negatively charged and the DNA is also negatively charged.

Magnetic bead-based extraction uses magnetic beads coated with nucleic acid binding agents, such as silica, oligo (dT), or carboxyl groups, to capture genomic DNA, RNA, plasmid DNA, and mitochondrial ...

Most nucleic acid extraction kits use spin-column technology, where DNA or RNA binds to a silica-based membrane in the presence of high concentrations of chaotropic salts, such as guanidine ...

A peptide nucleic acid (turquoise backbone) can bind to a strand of DNA (orange backbone) if their nucleobase sequences are complementary. Credit: J. Am. Chem. Soc.

Nucleic acids are chains of nucleotides that are a vital part of all living beings. The two most common types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), which ...

Results and discussion Table 2 displays an overview of the Acclaro Contaminant ID data acquired for nine mixtures containing DNA and varying levels of contamination (protein in this instance). As ...

An Osaka Metropolitan University-led research team has found that compounds in the nucleic acids derived from food can inhibit the growth of certain cancer cells.