Second, there are conflicting data on the effects of RAAS inhibition on ACE2 expression and how it relates to clinical outcomes in COVID-19, including the potential for ACE inhibitors and ARBs to ...

Reference Petrykiv SI, Laverman GD, Persson F, Vogt L, et al. Renin-angiotensin-aldosterone system intervention. Clin J Am Soc Nephrol 2017;12. doi: 10.2215/CJN.00390117 ...

Use of renin-angiotensin-aldosterone system (RAAS) blockers (ACE inhibitors, angiotensin receptor blockers, and aldosterone blockers) and diuretics was significantly associated with 1.6- and 1.5 ...

The renin–angiotensin–aldosterone system (RAAS) is an elegant cascade of vasoactive peptides that orchestrate key processes in human physiology. Severe acute respiratory syndrome coronavirus 1 ...

Finally, as COVID-19 has a strong component of ACE2 depletion underlying the course of the illness, and as RAAS (angiotensin and aldosterone) stressors promote cytokine-mediated disease in the lungs ...